Extended Data Fig. 6: Comparison of dynGMPPCP and dynAPO at interface G2.
From: Cryo-EM of the dynamin polymer assembled on lipid membrane
a, A large swing in the BSE of the tetramer in the apo conformation (PDB ID: 5A3F) disrupts interface G2. The apo tetramer and cryo-EM dynGMPPCP structure (GMPPCP-bound conformation) were aligned by the stalk. Curved arrow indicates the movement of the G domain. Domains are coloured green for GTPase, pink for BSE, blue for stalk in monomer B, and purple for GTPase, orange for BSE, tan for stalk in monomer A. b, Interface G2, coloured as above, in cryo-EM map of dynGMPPCP (grey mesh).
