Extended Data Fig. 2: NPF structure.
From: Structures of filaments from Pick’s disease reveal a novel tau protein fold
a, Fourier shell correlation curves between two independently refined half-maps (black line) and between the cryo-EM reconstruction and refined atomic model (red line). b, Local resolution estimates for the NPF reconstruction. c, Helical axis views of the NPF reconstruction. d, Close-up views of the cryo-EM map with the atomic model overlaid. The top row shows the three Pro-Gly-Gly-Gly (PGGG) motifs; the bottom row shows several amino acids with large side chains.
