Extended Data Table 2 Off-target sites identified by CIRCLE-seq for gP, gM and gMH that exhibit single nucleotide polymorphisms or indels based on CIRCLE-seq data

From: In vivo CRISPR editing with no detectable genome-wide off-target mutations

  1. Mismatches relative to the on-target site are shown as lower-case letters. Single nucleotide polymorphisms or indels that differ from the C57BL/6N mouse strain are shown as red-coloured letters. Targeted amplicon sequencing of sites for gM (first row) was performed with the same genomic DNA from wild-type and knock-in mice used for CIRCLE-seq experiments (data in Supplementary Table 7). N.D. = not done.
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