Extended Data Fig. 4: Overall architecture of TRPM2.
From: Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium
a, Domain organization of TRPM2. Dashed lines and cylinders denote regions that have not been modelled. b, c, Cartoon representation of one subunit of the EDTA–TRPM2 structure. d, e, Cartoon representation of one subunit of the ADPR/Ca2+–TRPM2 structure. ADPR and Ca2+ are shown as spheres.
