Extended Data Fig. 3: Structural analysis of the SprA complex components.
From: Type 9 secretion system structures reveal a new protein transport mechanism
a, Structural alignment of SprA-bound proteins against the homology models used in initial sequence docking. b, Access routes to the SprA pore viewed from the periplasm (top) or towards the lateral opening (bottom). In the PorV complex two loops involved in coordinating PorV occlude the lateral opening. The step domain is poorly ordered in the Plug complex. For clarity, PorV, Plug, and PPI are not shown. c, The PorV barrel is tilted relative to the SprA barrel. Aromatic residues on the surface of PorV are shown in green spacefill.
