Extended Data Fig. 6: Superposition of individual subunits from ALP-bound and DZP-bound α1β3γ2L GABAA receptor structures. | Nature

Extended Data Fig. 6: Superposition of individual subunits from ALP-bound and DZP-bound α1β3γ2L GABAA receptor structures.

From: GABAA receptor signalling mechanisms revealed by structural pharmacology

Extended Data Fig. 6

Superposition of the individual subunits from the DZP-bound (grey) and ALP-bound (α1, red; β3, blue; γ2, yellow) GABAA receptor structures. r.m.s.d. values are in the range of 0.38–0.41 Å for α1 (343–344 equivalent Cα positions), 0.37–0.40 Å for β3 (334–336 equivalent Cα positions) and 0.47 Å for γ2 subunits (330 equivalent Cα positions). Loops-C are marked by arrows.

Back to article page