Extended Data Fig. 2: Capturing early differentiation by pooled sequencing of indels generated within an E9.5 embryo.

Scatter plots of indel proportions from dissected bulk tissue of an E9.5 embryo. Placenta is the most distantly related from embryonic tissues, followed by the yolk sac; the three embryonic compartments share the highest similarity. n, number of indels used in the comparison; r, Pearson correlation of the relative indel proportions. Each of the three sites is considered independently per intBC. A heat map representing the correlation coefficients appears in Fig. 2b.