Extended Data Table 3 Results of neutralization assays in TZM-bl cells

From: Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques

  1. a, Results of neutralization assays in TZM-bl cells using the serum of eight macaques primed with VLP-RC1-4fill and the serum from a naive macaque at 1:25 dilution against two tier-2 HIV-1 isolates. ID50, half-maximum inhibitory dose; NHP, non-human primate. b, Results of neutralization assays in TZM-bl cells using the serum from eight macaques primed with VLP-RC1-4fill at 1:50 dilution against the fully glycosylated and glycan-deleted JRCSF.JB and BG505/T332N HIV-1 isolates. c, Results of neutralization assays in TZM-bl cells using monoclonal antibodies isolated from macaques primed with VLP-RC1-4fill at a 1:20 dilution of an antibody solution at 1.5 mg ml−1 (Ab988NHP), 1 mg ml−1 (Ab893NHP, Ab876NHP and Ab936NHP) or 0.5 mg ml−1 (Ab935NHP, Ab934NHP and Ab1170NHP). Values are the serum dilution at which relative luminescence units were reduced to 50% compared to virus control wells (no test sample).
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