Extended Data Fig. 4: Surface-marker profiles of recruited memory B cells in the vagina. | Nature

Extended Data Fig. 4: Surface-marker profiles of recruited memory B cells in the vagina.

From: Migrant memory B cells secrete luminal antibody in the vagina

Extended Data Fig. 4

C57BL/6 mice immunized with TK HSV-2 five weeks previously were challenged with wild-type HSV-2. a, Eighteen hours later, CD80 and PD-L2 expression on both IgD+ and IgD B cells in vaginal tissues was analysed by flow cytometry. b, The number of CD80+PD-L2+ memory B cells in the vagina at 18 h after secondary challenge was analysed by flow cytometry (naive, n = 2 mice; immune, n = 4 mice). Data are mean ± s.e.m. Data are representative of two independent experiments. Statistical significance was analysed by two-tailed Mann–Whitney U test.

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