Table 1 Summary of the history and definitions of epigenetics
From: Advances in epigenetics link genetics to the environment and disease
Authors | Epigenetics is the study of: | References |
|---|---|---|
Waddington | the processes by which the genotype brings the phenotype into being | |
Nanney | the systems that regulate the expression of the ‘library of specificities’ (that is, the genetic material, which is meant to be the DNA or RNA sequence) | |
Riggs, Holliday, Martienssen, Russo | mitotically and/or meiotically heritable changes in gene function that cannot be explained by changes in DNA sequence | |
Bird | structural adaptations of chromosomal regions so as to register, signal or perpetuate altered activity states | |
Greally, Lappalainen | properties of a cell, mediated by genomic regulators, that confer on the cell the ability to remember a past event. | |
Nicoglou | various intracellular factors that have an effect on the stability of developmental processes through their action on genome potentialities |
