Extended Data Fig. 9: Comparative metabolic effects of methionine restriction across mouse models and humans.
From: Dietary methionine influences therapy in mouse cancer models and alters human metabolism
a, Spearman’s rank correlation coefficients of fold changes of methionine-related metabolites induced by methionine restriction (defined in Extended Data Fig. 3f) in plasma samples from non-tumour bearing C57BL/6J mice, CRC119 and CRC240 mouse models, the sarcoma mouse model and healthy human subjects. b, Spearman’s rank correlation coefficients among different models in a, ranked from the highest to the lowest.
