Extended Data Fig. 9: Infiltrating monocytes recognize cyclical hydrostatic pressure in the lung via PIEZO1 to trigger neutrophil-mediated bacterial clearance.
From: Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity
Recruited monocytes recognize cyclical force via PIEZO1 in the lung and secrete EDN1 to drive HIF1α stabilization and CXCL2 expression to induce neutrophilia and bacterial clearance.
