Extended Data Fig. 5: Locations and cortical projection patterns from thalamic tracer experiments.

a, Locations of the thalamic tracer injection centroids (blue dots) mapped onto virtual 2D coronal planes from the Allen CCFv3. To minimize the number of sections shown, all centroids are mapped within 200 μm of their original location. See Supplementary Table 1 (thalamus tab) for more details on Cre lines and coverage. b, Example TC projections are shown in a flat map view of the ipsilateral cortical hemisphere for different thalamic nuclei arranged by the clusters identified in Fig. 3 and related to cortical modules. Most thalamic clusters projected primarily to a single module (Fig. 3c), but some thalamic regions projected across multiple modules (for example, anteroventral nucleus (AV), ventral anterior-lateral complex (VAL), parafascicular nucleus (PF), and central lateral nucleus (CL)), or projected strongly to both prefrontal and another module; for example, somatomotor (mediodorsal nucleus (MD)-1, ventral medial nucleus (VM)), lateral (paraventricular nucleus (PVT), MD-2, parataenial nucleus (PT)) or medial regions (nucleus of reuniens (RE), anteromedial nucleus (AM)).