Extended Data Fig. 4: Phosphoprotein tetramer in complex with L.

a, The L protein (cyan) is represented as a molecular surface and the tetrameric P protein subunits are represented as ribbons, following the colour codes in Figs. 1–3. b, Structures adopted by the four individual P subunits bound to L, coloured as a blue-to-red rainbow from the N- to the C-terminal end. Secondary structures boundaries are noted for each subunit. c, d, Superposition of the tetramerization helices in the context of the L:P complex and the free P protein. Structures are represented as coloured ribbons with the free phosphoprotein coiled-coil (PDB 4BXT) coloured in grey and the four P subunits reported in this study coloured according to Fig. 1. The r.m.s.d. of the superimposition is 1.13 Å over 88 α-carbon atoms. e, View of the complex in which L and P have been pulled apart to display electrostatic surfaces. f, Overall view of the L:P complex with P shown as ribbons and L as electrostatic surface. The P tetramer consists of subunits P1 (magenta), P2 (hot pink), P3 (salmon) and P4 (pink).