Extended Data Fig. 1: KRAS4A binds to HK2 in an isoform-specific and GTP-dependent manner. | Nature

Extended Data Fig. 1: KRAS4A binds to HK2 in an isoform-specific and GTP-dependent manner.

From: KRAS4A directly regulates hexokinase 1

Extended Data Fig. 1: KRAS4A binds to HK2 in an isoform-specific and GTP-dependent manner.

The indicated Flag-tagged RAS constructs (with or without G12V mutations) were expressed in HeLa cells and immunoprecipitated with anti-Flag beads. Blots were probed for Flag-tagged proteins and endogenous HK2. Flag–RAC1(Q61L) served as the negative control. The immunoblot shown is representative of four independent experiments.

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