Extended Data Fig. 1: Cntnap2, Fmr1 and Shank3 mutant mice show variable sociability performance.
From: IL-17a promotes sociability in mouse models of neurodevelopmental disorders
a, Sociability performance. MIA, n = 13; wild-type, n = 22; Cntnap2 mutant, n = 71; Fmr1 mutant, n = 165; Shank3 mutant, n = 50; from 30 independent experiments. b, Time spent investigating social (S) versus inanimate (I) objects for mice described in a. c, d, Total interaction time (c) and distance travelled (d) during the three-chambered sociability experiments described in a. All n values refer to the number of mice used. Statistics calculated by one-way ANOVA with Dunnett’s post-hoc test (a, c, d) or two-way ANOVA with Dunnett’s post-hoc test (b). Graphs are mean ± s.e.m.
