Extended Data Fig. 1: Chemosensory protein cluster.
From: A sensory appendage protein protects malaria vectors from pyrethroids
a, Schematic of the region surrounding the shared haplotype block found in the Anopheles gambiae 1000 Genomes Project data with all chemosensory proteins in the cluster highlighted in yellow. Genes displayed in order of appearance, from left to right, are as follows: AGAP008046, AGAP013713, AGAP008047, AGAP008048, AGAP008049, AGAP008050, AGAP008051 (SAP1), AGAP008052 (SAP2), AGAP008053, AGAP008054 (SAP3), AGAP008055 (CSP3), AGAP008056, AGAP029127 (CSP5, previously AGAP008058), AGAP008059 (CSP1), AGAP008060, AGAP008061 and AGAP008062 (CSP4). b, cDNA bootstrap consensus tree inferred from 1,000 replicates using the maximum likelihood method; the percentage of replicate trees with the associated clustering are shown next to the branches. Yellow indicates the sensory appendage proteins, orange the remaining chemosensory proteins in the 3R cluster and black dotted lines show CSP6, which is located on 2R. Alternative isoforms are represented with ‘-RX’, with ‘X’ proceeding alphabetically dependent on number of splice variants.
