Extended Data Fig. 8: Effects of stimulation of thalamocortical terminals on cortical firing rates and behaviour.
From: Cortical pattern generation during dexterous movement is input-driven
a, Firing rates and spike rasters for two example neurons at each stimulation frequency. b, Firing rates in the 2 s before stimulation versus the 2 s during stimulation at each stimulation frequency. Each point is a single neuron (n = 288 cells). c, Left, single-trial hand position and neural activity (first two principal components) for control trials in the dataset shown in Fig. 4b. Right, hand position and neural activity in the same session under optogenetic stimulation of thalamocortical terminals at 4 Hz, 10 Hz and 40 Hz. d, Probability that a lift is initiated within the first 500 ms of the cue on control trials and at each stimulation frequency. Each curve shows a single session (n = 6 sessions, n = 3 mice). Corresponding data in Fig. 4.
