Extended Data Fig. 6: Sequence analyses of RHPs.
From: Single-chain heteropolymers transport protons selectively and rapidly
a, Statistical distribution of number of OEGMA monomers per RHP1 chains in the 4,500 simulated RHP1 sequences (DP = 130). This distribution reflects the compositional dispersity in RHP1 chains. b, Statistical size distribution of hydrophobic segments with one OEGMA in RHP1s of various chain lengths ranging from DP = 40 to 200. The number of chains (4,500) was kept constant for each DP analysis. c, Normalized profiles of the size distribution in b. d, Number of hydrophobic segments per chain at various chain lengths. The counted hydrophobic segments here contain one OEGMA with segment size ≥11. e, Statistical size distributions of blocks of EHMA (pink) and MMA (red) within hydrophobic segments containing one OEGMA in RHP variants. Results are shown for hydrophobic segments with segment size ≥11. f, Schematic illustration of five EHMA monomers distributed at the end of an inserted RHP1 chain in a molecular dynamics simulation. EHMA, MMA and OEGMA are coloured pink, red and blue, respectively. Lipids are omitted for clarity.
