Extended Data Fig. 6: Pharmacological responses exhibited by endogenous ligands GLP-1 and oxyntomodulin in the presence of TT-OAD2.
From: Activation of the GLP-1 receptor by a non-peptidic agonist
Signalling profiles of GLP-1 and oxyntomodulin, after 30 min preincubation of vehicle (0) or increasing concentrations of TT-OAD2. Data were performed in HEK293A cells stably expressing the GLP-1R, and are mean + s.e.m. of 3–4 independent experiments performed in duplicate.
