Extended Data Fig. 3: The SICs exhibit strongly different TMEs. | Nature

Extended Data Fig. 3: The SICs exhibit strongly different TMEs.

From: B cells are associated with survival and immunotherapy response in sarcoma

Extended Data Fig. 3: The SICs exhibit strongly different TMEs.The alternative text for this image may have been generated using AI.

This figure refers to the GSE21050 cohort (n = 283). a, Composition of the GSE21050 cohort by SIC, histology and site of disease. b, Composition of the TME by SIC as defined by the MCP-counter Z-scores. c, Expression of gene signatures related to the functional orientation of the immune TME by SIC. d, Expression of genes related to immune checkpoints by SIC. Adjusted P values are obtained from Benjamini–Hochberg correction of two-sided Kruskal–Wallis test P values. These observations stand for cohorts GSE21122 and GSE30929 (not shown).

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