Extended Data Fig. 1: Characterization of genetic drivers of LUSC tumorigenesis. | Nature

Extended Data Fig. 1: Characterization of genetic drivers of LUSC tumorigenesis.

From: Elevated NSD3 histone methylation activity drives squamous cell lung cancer

Extended Data Fig. 1: Characterization of genetic drivers of LUSC tumorigenesis.

a, Genetic alterations and mRNA expression of genes in the 8p11–12 amplification genomic region of chromosome 8 from the 85 specimens of 8p11–12-amplified human LUSC in the TCGA dataset. b, Genetic alterations and mRNA expression of NSD3, FGFR1, PIK3CA, PTEN, SOX2, CDKN2A and CDKN2B from all 464 of the human LUSC specimens in the TCGA dataset (ID: phs000178) analysed using cBioPortal.

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