Extended Data Fig. 7: Functional connections between visual cortical areas.

a, Peak offset distributions aggregated across 25 mice for each area combination, during drifting gratings presentation. The total number of pairs (n) is labelled in each sub-panel. Dashed black line indicates zero time lag. Dashed red line indicates the median of the distribution. b, Fraction of within- and between-area unit pairs exhibiting sharp peaks, out of all simultaneously recorded pairs. c, Combined median of peak offsets across mice (averaged across mice; n = 25 mice in total) for each pair of cortical areas. d, Correlation between the median peak offset and the difference in hierarchy scores among 21 pairs (lower triangle and diagonal of the matrix). e, Relationship between average 3D Euclidean distance between units simultaneously recorded in each pair of areas (following registration to the CCFv3) and their hierarchy score difference. r_P, Pearson correlation coefficient; r_S, Spearman’s rank correlation coefficient. f, Average number of sharp peak connections per mouse for jitter-corrected CCGs calculated during spontaneous activity (30 min grey screen period). Pixels masked with grey indicate no sharp peaks were detected. g, Average directionality score across mice during spontaneous activity.