Extended Data Fig. 5: BIR stalls inside ITS.
From: Tracking break-induced replication shows that it stalls at roadblocks
a, AMBER analysis of BIR synthesis in TLC1 and tlc1Δ cells traversing (ITS)~40, similar to Fig. 3b, c, but with nocodazole added 6hr post DSB. The means ± s.d. (n = 3 independent biological repeats) are indicated. **Statistical difference is determined by t-test (two-tailed), P = 0.0053. b, Proposed model of BIR interruption at ITS followed by telomerase-mediated de novo telomere addition.
