Extended Data Fig. 7: Manhattan plots of seven somatic eGenes associated with genic lead burden.

Altogether, 11 genic somatic eQTLs showed significant changes in gene expression associated with somatic burdens within the gene boundaries (intronic or exonic). The seven genes shown here are known to be important in the pathogenesis of specific cancers. a, CDK12. b, PI4KA. c, IRF4. d, AICDA. e, C11orf73 (also known as HIKESHI). f, BCL2. g, SGK1.