Extended Data Fig. 7: Intravenous administration of AAV vectors does not elicit an inflammatory response or intestinal dysmotility.
From: Neuronal programming by microbiota regulates intestinal physiology
a, Cross-sections from the colon of wild-type (top), wild-type infected with AAV9-CaMKII-Cre (middle) and Ahr fl/fl (bottom) mice stained with Alcian blue–PAS (left) or haematoxylin and eosin (H&E) (right). Data represent two independent experiments. b, Graph (mean ± s.d.) shows that administration of AAV-CaMKII-Cre vector into wild-type mice is not sufficient to alter intestinal transit time. n = 3 (wild type), 4 (WT + AAV) or 3 (Ahr fl/fl) mice. Statistical test is a two-sided non-parametric Mann–Whitney U-test. Scale bars, 50 μm.
