Extended Data Fig. 3: Baseline correction of dopamine fMRI data using T2*-dependent signals.
From: Local and global consequences of reward-evoked striatal dopamine release
a, Echo time dependence of the slow component of the fMRI signal recorded in the presence of the 9D7 dopamine sensor in the ventral striatum. Variation of the slow positive signal with TE provides a basis for extracting the baseline time course using the ME-ICA approach. Error margins are omitted for graphical clarity. b, Quantitative maps of dopamine release formed after baseline correction using the ME-ICA signal. Features correspond closely to the maps in Fig. 2a, which were corrected using a baseline derived from the control BM3h-WT T1-weighted fMRI data, indicating that the choice of baseline correction method makes little difference to the outcome.
