Extended Data Fig. 3: In situ hybridization data from the Allen Mouse Brain Atlas confirms layer-5b-specific mRNA expression of genes highly enriched by TRAP from intact Glt25d2-eGFP-L10a mice. | Nature

Extended Data Fig. 3: In situ hybridization data from the Allen Mouse Brain Atlas confirms layer-5b-specific mRNA expression of genes highly enriched by TRAP from intact Glt25d2-eGFP-L10a mice.

From: Injured adult neurons regress to an embryonic transcriptional growth state

Extended Data Fig. 3: In situ hybridization data from the Allen Mouse Brain Atlas confirms layer-5b-specific mRNA expression of genes highly enriched by TRAP from intact Glt25d2-eGFP-L10a mice.The alternative text for this image may have been generated using AI.

a, Fold change of most highly enriched mRNA transcripts in the corticospinal cell population (TRAPed samples) compared to mRNA from whole motor cortex (unbound samples) in the intact state. n = 3 biological replicates per condition. b, In situ hybridization (ISH) data (Allen Mouse Brain Atlas; https://mouse.brain-map.org/) of most highly enriched genes (from a) confirms cell-type-specific enrichment of TRAPed mRNA expression in layer-5b neurons of the adult mouse motor cortex.

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