Extended Data Fig. 3: Phylogenetic trees of endometrial glands for donors aged 42 to 81 years. | Nature

Extended Data Fig. 3: Phylogenetic trees of endometrial glands for donors aged 42 to 81 years.

From: The mutational landscape of normal human endometrial epithelium

Extended Data Fig. 3: Phylogenetic trees of endometrial glands for donors aged 42 to 81 years.The alternative text for this image may have been generated using AI.

Phylogenetic trees for twelve donors aged 42 to 81 years were also reconstructed using SBSs with branch length proportional to the number of variants; the stacked bar plots represent the attributed SBS mutational signatures that contributed to each branch. Signature extraction was not performed on branches with fewer than 100 substitutions. The ordering of signatures within each branch is for visualization purposes only. Every single studied gland from donors PD39952 (44 year old) and PD40659 (81 year old) had at least one driver mutation.

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