Extended Data Fig. 2: Assessment of Hoxb13-KO and Hoxb13-iKO hearts post-MI.
From: A calcineurin–Hoxb13 axis regulates growth mode of mammalian cardiomyocytes
a, Schematic of MI model in Hoxb13-KO mice. b–d, Representative echocardiography (b), heart weight/body weight (c), and wet-to-dry lung weight ratio (d) in Hoxb13-KO mice 16 weeks after MI. e, Representative serial Masson’s trichrome staining in transversal sections (left) and quantification of fibrotic scars (right) in Hoxb13-KO MI hearts at 16 weeks after injury. f, Schematic of MI model in Hoxb13-iKO mice. g, h, Heart weight/body weight (g) and wet-to-dry lung weight ratio (h) in Hoxb13-iKO mice 16 weeks after MI. i, Serial echocardiography of Hoxb13-iKO MI and sham mice. Data are mean ± s.e.m.; unpaired two-sided t-test. **P < 0.01, ***P < 0.001; n.s., not significant. For n values, see Methods. Scale bar 1 mm (e).
