Extended Data Fig. 2: Overview of border gene organization and pericentromere size. | Nature

Extended Data Fig. 2: Overview of border gene organization and pericentromere size.

From: Convergent genes shape budding yeast pericentromeres

Extended Data Fig. 2: Overview of border gene organization and pericentromere size.

a, Diagram showing the positions of convergent gene pairs flanking centromeres. Grey ovals represent the centromeres; convergent gene pairs at borders are indicated by arrows. b, Genomic distances (thick grey lines) between the 3′ ends of convergent genes (black and orange arrows) at borders, as well as the 3′ and 5′ ends of the two genes transcribed towards centromeres (black arrows) (n = 49). Centre line, median; box limits, second and third quartiles; whiskers, first and fourth quartiles. c, Table of convergent genes identified at pericentromere borders for each chromosome, along with the corresponding pericentromere size. A border was defined as the innermost cohesin peak near the centromere that persisted in the presence of tension. d, Pericentromere sizes determined in c are plotted against chromosome size. e, Percentages of genes essential for growth on rich glucose media among genes at borders and among all genes. f, Scc1 ChIP-seq in asynchronous C. glabrata cells, showing chromosome F from ref. 13.

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