Extended Data Fig. 4: Flowchart for structural determination.
From: Structural basis for catalysis and substrate specificity of human ACAT1
a, Flowchart of data processing; see Methods for details. b, Electron microscopy maps of representative structural elements. The densities, contoured at 10–13σ, were prepared in PyMOL. c, Structure of an ACAT1 protomer. The structure is rainbow-coloured on the left (blue for the amino terminus and red for and the carboxyl terminus) and domain-coloured on the right. d, Topological structure of ACAT1. The structural elements are colour-coded to match the domain colours in c.
