Extended Data Fig. 5: Analysis of cytokine expression in WT and Enh-KO mice treated with DSS.
From: A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells
a, Replicate measurements of IFN-γ (left) and Foxp3 (right) in CD4+ T cells from large intestinal lamina propria (n = 8 mice per group). Data representative of two independent experiments. b–e, Concentration of the indicated cytokines in the serum of WT and Enh-KO mice treated with vehicle or DSS for 16 days. Data pooled from two independent experiments with n = 8, 8, 20 and 17 for WT (vehicle), Enh-KO (vehicle), WT (DSS), Enh-KO (DSS) groups. Data analysed using unpaired two-tailed Student’s t test. Data are mean ± s.e.m.
