Extended Data Fig. 9: Binding of the monoclonal antibodies to the RBD of SARS-CoV-2 and cross-reactivity to SARS-CoV.

a, EC₅₀ values for binding to the RBD of SARS-CoV-2. Average of two or more experiments. n = 89. b, c, Binding curves (b; representative experiment) and EC₅₀ values (c; mean of two experiments) for binding to the RBD of SARS-CoV. n = 20 and n = 17 (excluding isotype and CR3022) for b and c, respectively. d, e, SARS-CoV pseudovirus neutralization curves and IC₅₀ values. d, Data are mean ± s.d. of duplicates for one representative experiment. e, Data are the mean of two experiments (n = 10, excluding CR3022). Samples with IC₅₀ values above 1 μg ml⁻¹ were plotted at 1 μg ml⁻¹.