Extended Data Fig. 5: Clinical correlates of neutralization.
From: Convergent antibody responses to SARS-CoV-2 in convalescent individuals
a, Normalized AUC for anti-RBD IgM plotted against NT50. r = 0.3119, P = 0.0001. b, Normalized AUC for anti-S IgM plotted against NT50. r = 0.3211, P < 0.0001. c, Duration of symptoms in days plotted against NT50. r = 0.1997, P = 0.0146. d, Time between symptom onset and plasma collection in days plotted against NT50. r = −0.1344, P = 0.1033. e, Symptom severity plotted against NT50. r = 0.2234, P = 0.0062. f, Age plotted against NT50. r = 0.3005, P = 0.0002. All correlations were analysed by two-tailed Spearman’s tests; n = 149. The dotted line (NT50 = 5) represents the lower limit of detection of the pseudovirus neutralization assay. Samples with neutralizing titres below 1:50 were plotted at the lower limit of detection.
