Extended Data Fig. 3: Phenotypic characterization of B-ALL cells driven by oncogenic STAT5 or ERK. | Nature

Extended Data Fig. 3: Phenotypic characterization of B-ALL cells driven by oncogenic STAT5 or ERK.

From: Signalling input from divergent pathways subverts B cell transformation

Extended Data Fig. 3: Phenotypic characterization of B-ALL cells driven by oncogenic STAT5 or ERK.

a–g, Eight different B-ALL PDX samples (Supplementary Table 5) were analysed by flow cytometry for surface expression of CRLF2 (a), VpreB (b), CD20 (c), IgM (d), Ig-κλ (e), CD34 (f) and IL7R (g). Normal CD19+ B-cell precursors from a normal human bone-marrow (BM) sample and mature B cells from a normal human peripheral blood (PB) sample, as well a mature B-cell lymphoma cell line (DLBCL), were used as references. Shown are representative FACS plots from three independent experiments.

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