Extended Data Fig. 3: Normalized CpG distributions for tuatara and other vertebrates.
From: The tuatara genome reveals ancient features of amniote evolution
Tuatara show a statistically significant bimodal normalized CpG distribution in all genomic regions examined (gene promoters, exons, introns and intergenic sequences). Explicit testing using mixed models uncovered global normalized CpG bimodality across all taxa, indicating that bimodality is ancestral and highly conserved across vertebrates irrespective of sex-determining mechanism. Further details are provided in Supplementary Information 8. Silhouettes are hand-drawn from the original photographs of A. Eckley, except for Anolis (D. Hobern, CC-BY-2.0), crocodile and hen (designed by Creazilla, https://creazilla.com/).
