Extended Data Fig. 8: Experimental schemes.
From: Mucosal or systemic microbiota exposures shape the B cell repertoire
This figure relates to Fig. 3. a, Schematic experimental design, related to Fig. 3d–g. Germ-free mice were mucosally primed with three doses of 1010 CFU E. coli HA107 or reversible S. typhimurium HA218 on alternate days or remained germ-free. At day 21, half of each group received a second schedule of priming, but with the opposite taxon. Recovery of germ-free status was verified after each stage. b, Schematic experimental design, related to Fig. 3h–k. As in a, except that both reversible taxa were given systemically at doses of 108 CFU, as shown.
