Extended Data Fig. 2: Bacterial loads and composition of the small-intestine microbiota, and phylogeny of OTU0002. | Nature

Extended Data Fig. 2: Bacterial loads and composition of the small-intestine microbiota, and phylogeny of OTU0002.

From: Gut microorganisms act together to exacerbate inflammation in spinal cords

Extended Data Fig. 2

a, Bacterial loads in the contents of the small intestine, as determined by qPCR of 16S rRNA (n = 5 mice). Data are mean ± s.d. ***P < 0.001, **P < 0.01, *P < 0.05. One-way ANOVA with Tukey’s test. Exact P values are in Source Data. b, Phylum-level relative abundance of small-intestine microbiota. c, Principal coordinate analysis plot of unweighted UniFrac distances. Each ellipse shows an 80% confidence interval (n = 5 mice). PC1, PC2, principle coordinates 1 and 2. d, Phylogenetic tree based on 16S rRNA gene sequences of OTU0002 and deposited isolates. e, Phylogenetic tree of OTU0002 and related uncultured bacteria. The bacterial reads from human faeces (human faeces 1 and 2) were retrieved from ref. 38 and ref. 6, respectively. f, Representative SEM images of the caecum and colon from OTU0002-monocolonized mice (n = 4).

Source data

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