Extended Data Fig. 7: Alignment of M1 protein sequences.
From: The native structure of the assembled matrix protein 1 of influenza A virus

M1 sequences of the following viruses: influenza A M1 PR8 (A/Puerto Rico/8/1934 (H1N1)), influenza A M1 HK68 (A/Hong Kong/1/1968 (H3N2)), influenza A M1 (A/chicken/Fujian/25/2000 (H9N2)), bat influenza M1 H17N10 (A/little yellow-shouldered bat/Guatemala/164/2009 (H17N10)), bat influenza M1 H18N11 (A/flat-faced bat/Peru/033/2010 (H18N11)), influenza B M1 (B/Lee/1940) were downloaded from UniProt and aligned using mafft (https://mafft.cbrc.jp/alignment/software/). Locations of α-helices 1–12 are marked above the amino acid sequences. Conserved histidines are shaded blue, and conserved charged residues are shaded cyan. Substituted histidine locations and compensatory histidine substitutions are shaded red.