Extended Data Fig. 2: PCP and MK801—but not memantine, saline or LSD—induce RSP-localized rhythms.
a, Quantification of oscillation frequency content before and after PCP injection, n = 5 mice. b, For PCP, example temporal video sequence of 410 nm-corrected fluorescence over 1 s in a Thy1-GCaMP6s mouse showing RSP rhythm. c, Quantification of oscillation frequency content before and after MK801 injection, n = 5 mice. d, For MK801, example temporal video sequence of 410 nm-corrected fluorescence over 1 s in a Thy1-GCaMP6s mouse, showing RSP rhythm. e, Quantification of oscillation frequency content before and after memantine injection, n = 5 mice. f, For memantine, example temporal video sequence of 410 nm-corrected fluorescence across 1 s in a Thy1-GCaMP6s mouse. Here, neither rhythms nor travelling waves are seen. g, Quantification of oscillation frequency content before and after saline injection, n = 5 mice. h, Quantification of mean power in 1–3 Hz band for saline (n = 5 mice), corrected two-sided paired t-tests (*P < 0.05, **P < 0.01, NS P > 0.05; Hedge’s g 0.36, 0.18, 0.14, 0.01). i, Quantification of oscillation frequency content before and after LSD injection, n = 5 mice. j, Quantification of mean power in 1–3 Hz band for LSD (n = 5 mice), corrected two-sided paired t-tests (*P < 0.05, **P < 0.01, NS P > 0.05; Hedge’s g LSD 2.05, 0.62, 1.07, 0.65). k, For LSD, example temporal video sequence of 410 nm-corrected fluorescence across 1 s in a Thy1-GCaMP6s mouse. Here, neither rhythms nor travelling waves are seen.
