Fig. 4: Translation of host and viral genes.
a, Translation levels of canonical viral ORFs in Vero E6 cells at 5 hpi and in Calu3 cells at 7 hpi. ORFs are ordered on the basis of their genomic location. b, Viral ORF translation levels, as calculated from ribosome densities for Vero E6 cells at 5 hpi. Solid fill represents canonical ORFs, and striped fill represents novel ORFs. c, Scatter plot of viral ORF expression in Vero E6 cells at 5 hpi and Calu3 cells at 7 hpi. Points representing canonical ORFs are outlined in black. d–f, Relative transcript abundance versus ribosome densities for each host and viral ORF at 5 hpi (d) and 24 hpi (e) in Vero E6 cells and at 7 hpi in Calu3 cells (f). Transcript abundance was estimated by counting the reads that span the corresponding junction and footprint densities were calculated from the CHX sample.
