Extended Data Fig. 5: Blockage of TGF-β signalling in CD4+ T cells promotes expansion of CD4+FOXP3− T cells in tumours. | Nature

Extended Data Fig. 5: Blockage of TGF-β signalling in CD4+ T cells promotes expansion of CD4+FOXP3− T cells in tumours.

From: TGF-β suppresses type 2 immunity to cancer

Extended Data Fig. 5

Representative flow cytometry plots of TCRβ, NK1.1, CD4, CD8 and FOXP3 expression and statistical analyses of the gated populations in tumour-infiltrating leukocytes from 23-week-old Tgfbr2fl/fl PyMT (WT; n = 9) and Thpok-cre;Tgfbr2fl/fl PyMT (KO; n = 9) mice. Data are represented as the mean ± s.e.m. (biologically independent mice). Two-tailed unpaired t-test.

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