Extended Data Fig. 3: Identification of the adult neuronal clusters. | Nature

Extended Data Fig. 3: Identification of the adult neuronal clusters.

From: Neuronal diversity and convergence in a visual system developmental atlas

Extended Data Fig. 3: Identification of the adult neuronal clusters.

a, Pearson correlation between the average log-normalized non-integrated expression of the top10 cluster markers of the adult dataset clusters (x axis) and the transcriptome of isolated neurons18,20. We represented Dm3, Tm9, T4 and T5 before their split into Dm3a/Dm3b, Tm9v/Tm9d, T4/T5ab and T4/T5cd. When two transcriptomes were published for a given neuronal type, the one presenting the highest correlation gap is displayed in this figure. R1–8, average gene expression of all photoreceptors20. KC, Kenyon cells; cluster 112 therefore probably corresponds to contamination from the central brain. b, Legend as in a but for LC cells. We indicated several matching clusters to highlight the high similarity between the transcriptomes of LC cells, which explains the lower correlation gaps observed for these neurons. c, Left, legend as in a but for Pm3 cells. Right, mixture modelling of Pm3 markers19 (y axis). Clusters are spread on the x axis, with the probability of expression of the markers figured by the size of the black dots.

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