Extended Data Fig. 9: The competitive fitness of the living ancestor.
From: A yeast living ancestor reveals the origin of genomic introgressions
a, Mitotic growth (absolute doubling time, h) of the living ancestor (n = 40) as compared to the closest extant relatives of its S. cerevisiae DBVPG6765 (top left, n = 8) and S. paradoxus N17 (top middle, n = 16) parents and a diploid experimental F1 hybrid between the two (top right, n = 16), the living ancestor’s diploid gametes (bottom left, n = 200) and backcrosses of its haploid-stable gametes to S. cerevisiae (bottom middle, n = 64) and S. paradoxus parents (bottom right, n = 64). The number of observations (n) results from the combination of the strains in each group and the number of replicates performed in the experiment. Significant differences enumerated in the main text are indicated by asterisks or name (two-tailed Welsh test, FDR q = 0.05) and presented in Supplementary Table 7. For the living ancestor gametes, we instead indicate (red text) the rare environments where no significant difference was found. b, The percentage of surviving cells (mean ± s.d.) for each step of the hybridization-to-introgression process during a 25-day chronological lifespan experiment. n = biologically independent samples. S. cerevisiae (n = 1), S. paradoxus (n = 2), experimental first-generation (F1) hybrid (n = 2), living ancestor (n = 1), living ancestor gametes (n = 25), backcross to S. cerevisiae (n = 8), backcross to S. paradoxus (n = 8), Alpechin (n = 16). c, Gating strategy used for the estimation of the percentage of surviving cells shown in b.
