Extended Data Fig. 4: GO enrichment analyses.

a–d, Top five significantly enriched GO terms among genes with high (a, b) and low (c, d) translational efficiency for brain (a, c; blue) and liver (b, d; green) in mouse. e, Top ten significantly enriched GO terms for each of the mouse spermatogenesis translational efficiency trajectory cluster (Extended Data Fig. 3h–k). f–h, Significantly enriched GO terms (biological processes) among genes that changed significantly more at the translatome compared to the transcriptome layer in brain (f), liver (g) and testis (h). Significance was estimated in Fisher’s exact test (P < 0.05), with P values adjusted for multiple testing using the Benjamini–Hochberg method.