Extended Data Fig. 6: Efficacy curve of imatinib, MPA and QNHC comparing VSVG and SARS-CoV-1-entry virus on hPSC-LOs.
From: Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
a, Chemical structure, efficacy curve and toxicity curve of two primary hit drug candidates, choloroquine and prochlorperazine. n = 3 biological independent experiments. b, Bright field+immunostaining images of SARS-CoV-2-entry virus infected hPSC-LOs. Scale bars = 50 μm. Microscale bars = 10 μm. c, Efficacy curve of imatinib, MPA and QNHC on VSVG virus. n = 3 biological independent experiments. d, Efficacy curve of imatinib, MPA and QNHC on SARS-CoV-1-entry virus. n = 3 biological independent experiments. Data are representative of at least three independent experiments.
