Extended Data Fig. 8: DEGs and potential cell–cell interactions in non-neuronal cells during memory consolidation.

a, Volcano plots of non-neuronal cell types when comparing cells in FR over NF nice. DEGs (FDR >0.01, log₂FC >1) are labelled in red, and exemplary DEGs (high log₂FC and log₁₀FDR) are labelled in black. b, Number of non-neuronal cells collected in this study, for each cell type and experimental condition. c, Heat map of a subset of neuronal ligands and glial receptors that are found to be differentially perturbed upon memory consolidation. Only receptors and ligands which were found to be (differentially) expressed are shown. d, Left, heat map of the log₂FC of DEGs (FR over NF) in neurons that are classified as ligands. Middle and right, Sankey plot of known ligand-receptor pairs and heat map of the average scaled expression level of the corresponding receptors in each cell type. e, Left, heat map of the log₂FC of DEGs (FR over NF) in neurons that are classified as receptors. Middle and right, Sankey plot of known ligand-receptor pairs and heat map of the average scaled expression level of the corresponding ligands in each cell type.