Extended Data Fig. 8: Contacts from CTCF sites are highly correlated with cohesin.

a, MCC profiles of four CTCF sites with low co-occupancy of cohesin as measured by RAD21 ChIP–seq. These sites form no peaks with surrounding CTCF sites. b, When high levels of RAD21 coincide with CTCF, the sites form multiple contacts with surrounding CTCF sites. Profiles are included for DNase-seq and ChIP–seq of CTCF and RAD21 in erythroid cells.