Extended Data Fig. 5: All state occupancy distributions.
From: cAMP binding to closed pacemaker ion channels is non-cooperative
a, b, Normalized state occupancy distributions for HCN1SM (a) and HCN2SM (b) across all recorded fcAMP concentrations. Each plot indicates the total number of molecules (n) and data points (that is, frames, m) included in the analysis. P is the success rate of the optimized binomial distribution considering four binding sites. All obtained and expected state occupancies values are in Supplementary Table 2.
